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期刊文献 > Elife期刊选择月份

Elife

2021 May 7

Hernandez-Lagana E(#), Mosca G(#), Mendocilla-Sato E(#)

2. Persistent effects of pair bonding in lung cancer cell growth in monogamous Peromyscus californicus.

Elife

2021 May 7

Naderi A, Soltanmaohammadi E, Kaza V

3. fMRI-based detection of alertness predicts behavioral response variability.

Elife

2021 May 7

Goodale SE, Ahmed N, Zhao C

4. Non-canonical Hedgehog signaling regulates spinal cord and muscle regeneration in Xenopus laevis larvae.

Elife

2021 May 6

Hamilton AM, Balashova OA, Borodinsky LN.

5. Dorsal periaqueductal gray ensembles represent approach and avoidance states.

Elife

2021 May 6

Reis FM(#), Lee JY(#), Maesta-Pereira S

6. Instantaneous movement-unrelated midbrain activity modifies ongoing eye movements.

Elife

2021 May 6

Buonocore A(#), Tian X(#), Khademi F

7. Endogenous p53 expression in human and mouse is not regulated by its 3'UTR.

Elife

2021 May 6

Mitschka S, Mayr C.

8. 4-Hydroxy-2-nonenal antimicrobial toxicity is neutralized by an intracellular pathogen.

Elife

2021 May 6

Tabakh H, McFarland AP, Thomason MK

9. CM1-driven assembly and activation of yeast γ-tubulin small complex underlies microtubule nucleation.

Elife

2021 May 5

Brilot AF, Lyon AS, Zelter A

10. SAM homeostasis is regulated by CFI(m)-mediated splicing of MAT2A.

Elife

2021 May 5

Scarborough AM, Flaherty JN, Hunter OV

11. Genetic variation, environment and demography intersect to shape Arabidopsis defense metabolite variation across Europe.

Elife

2021 May 5

Katz E, Li JJ, Jaegle B

12. Combinatorial deployment of F-actin regulators to build complex 3D actin structures in vivo.

Elife

2021 May 5

Xie Y, Budhathoki R, Blankenship JT.

13. The LRR-TM protein PAN-1 interacts with MYRF to promote its nuclear translocation in synaptic remodeling.

Elife

2021 May 5

Xia SL(#), Li M(#), Chen B

14. Disruption of entire Cables2 locus leads to embryonic lethality by diminished Rps21 gene expression and enhanced p53 pathway.

Elife

2021 May 5

Dinh TTH(#), Iseki H(#), Mizuno S(#)

15. Ir56d-dependent fatty acid responses in Drosophila uncover taste discrimination between different classes of fatty acids.

Elife

2021 May 5

Brown EB, Shah KD, Palermo J

16. Linking mPFC circuit maturation to the developmental regulation of emotional memory and cognitive flexibility.

Elife

2021 May 5

Klune CB(#), Jin B(#), DeNardo LA.

17. Mapping single-cell atlases throughout Metazoa unravels cell type evolution.

Elife

2021 May 4

Tarashansky AJ, Musser JM(#), Khariton M(#)

18. Sec17/Sec18 can support membrane fusion without help from completion of SNARE zippering.

Elife

2021 May 4

Song H, Torng TL, Orr AS

19. OPA1 deletion in brown adipose tissue improves thermoregulation and systemic metabolism via FGF21.

Elife

2021 May 4

Pereira RO, Marti A, Olvera AC

20. Co-targeting myelin inhibitors and CSPGs markedly enhances regeneration of GDNF-stimulated, but not conditioning-lesioned, sensory axons into the spinal cord.

Elife

2021 May 4

Zhai J, Kim H, Han SB

21. Qki regulates myelinogenesis through Srebp2-dependent cholesterol biosynthesis.

Elife

2021 May 4

Zhou X(#), Shin S(#), He C(#)

22. Sniff-synchronized, gradient-guided olfactory search by freely moving mice.

Elife

2021 May 4

Findley TM(#), Wyrick DG(#), Cramer JL

23. Computational modeling identifies embolic stroke of undetermined source patients with potential arrhythmic substrate.

Elife

2021 May 4

Bifulco SF, Scott GD, Sarairah S

24. DRAXIN regulates interhemispheric fissure remodelling to influence the extent of corpus callosum formation.

Elife

2021 May 4

Morcom L(#), Edwards TJ(#), Rider E

25. Multiple lineages of Streptomyces produce antimicrobials within passalid beetle galleries across eastern North America.

Elife

2021 May 4

Pessotti RC, Hansen BL, Reaso JN

26. Autism-associated SHANK3 missense point mutations impact conformational fluctuations and protein turnover at synapses.

Elife

2021 May 4

Bucher M, Niebling S, Han Y

27. Fully autonomous mouse behavioral and optogenetic experiments in home-cage.

Elife

2021 May 4

Hao Y, Thomas AM, Li N.

28. Metabolic flexibility via mitochondrial BCAA carrier SLC25A44 is required for optimal fever.

Elife

2021 May 4

Yoneshiro T, Kataoka N, Walejko JM

29. Linguistic processing of task-irrelevant speech at a cocktail party.

Elife

2021 May 4

Har-Shai Yahav P, Zion Golumbic E.

30. Receptor-mediated mitophagy regulates EPO production and protects against renal anemia.

Elife

2021 May 4

Geng G(#), Liu J(#), Xu C(#)

31. Reduced purine biosynthesis in humans after their divergence from Neandertals.

Elife

2021 May 4

Stepanova V(#), Moczulska KE(#), Vacano GN(#)

32. Permeant fluorescent probes visualize the activation of SARM1 and uncover an anti-neurodegenerative drug candidate.

Elife

2021 May 4

Li WH, Huang K, Cai Y

33. Integrating taxonomic, functional, and strain-level profiling of diverse microbial communities with bioBakery 3.

Elife

2021 May 4

Beghini F(#), McIver LJ(#), Blanco-Míguez A

34. Metabolic biomarker profiling for identification of susceptibility to severe pneumonia and COVID-19 in the general population.

Elife

2021 May 4

Julkunen H, Cichońska A, Slagboom PE

35. Multiplexed mRNA assembly into ribonucleoprotein particles plays an operon-like role in the control of yeast cell physiology.

Elife

2021 May 4

Nair RR(#), Zabezhinsky D(#), Gelin-Licht R

36. Mesoscale phase separation of chromatin in the nucleus.

Elife

2021 May 4

Bajpai G, Amiad Pavlov D, Lorber D

37. Whole-genome sequencing analysis of semi-supercentenarians.

Elife

2021 May 4

Garagnani P(#), Marquis J(#), Delledonne M(#)

38. Inflammation drives alternative first exon usage to regulate immune genes including a novel iron-regulated isoform of Aim2.

Elife

2021 May 28

Robinson EK(#), Jagannatha P(#), Covarrubias S

39. A sustained type I IFN-neutrophil-IL-18 axis drives pathology during mucosal viral infection.

Elife

2021 May 28

Lebratti T(#), Lim YS(#), Cofie A

40. Development and validation of a nomogram to better predict hypertension based on a 10-year retrospective cohort study in China.

Elife

2021 May 28

Deng X(#), Hou H(#), Wang X

41. VASP-mediated actin dynamics activate and recruit a filopodia myosin.

Elife

2021 May 27

Arthur AL, Crawford A, Houdusse A

42. An excitatory lateral hypothalamic circuit orchestrating pain behaviors in mice.

Elife

2021 May 27

Siemian JN, Arenivar MA, Sarsfield S

43. A high rate of COVID-19 vaccine hesitancy in a large-scale survey on Arabs.

Elife

2021 May 27

Qunaibi EA, Helmy M, Basheti I

BACKGROUND: Vaccine hesitancy can limit the benefits of available vaccines in halting the spread of COVID-19 pandemic. Previously published studies paid little attention to Arab countries, which has a population of over 440 million. In this study, we present the results of the first large-scale multinational study that measures vaccine hesitancy among Arab-speaking subjects. METHODS: An online survey in Arabic was conducted from 14 January 2021 to 29 January 2021. It consisted of 17 questions capturing demographic data, acceptance of COVID-19 vaccine, attitudes toward the need for COVID-19 vaccination and associated health policies, and reasons for vaccination hesitancy. R software v.4.0.2 was used for data analysis and visualization. RESULTS: The survey recruited 36,220 eligible participants (61.1% males, 38.9% females, mean age 32.6 ± 10.8 years) from all the 23 Arab countries and territories (83.4%) and 122 other countries (16.6%). Our analysis shows a significant rate of vaccine hesitancy among Arabs in and outside the Arab region (83% and 81%, respectively). The most cited reasons for hesitancy are concerns about side effects and distrust in health care policies, vaccine expedited production, published studies and vaccine producing companies. We also found that female participants, those who are 30-59 years old, those with no chronic diseases, those with lower level of academic education, and those who do not know the type of vaccine authorized in their countries are more hesitant to receive COVID-19 vaccination. On the other hand, participants who regularly receive the influenza vaccine, health care workers, and those from countries with higher rates of COVID-19 infections showed more vaccination willingness. Interactive representation of our results is posted on our project website at https://mainapp.shinyapps.io/CVHAA. CONCLUSIONS: Our results show higher vaccine hesitancy and refusal among Arab subjects, related mainly to distrust and concerns about side effects. Health authorities and Arab scientific community have to transparently address these concerns to improve vaccine acceptance. FUNDING: This study received no funding.

44. Spontaneous neural synchrony links intrinsic spinal sensory and motor networks during unconsciousness.

Elife

2021 May 27

McPherson JG, Bandres MF.

45. RSC primes the quiescent genome for hypertranscription upon cell-cycle re-entry.

Elife

2021 May 27

Cucinotta CE, Dell RH, Braceros KC

46. SIRT1 regulates sphingolipid metabolism and neural differentiation of mouse embryonic stem cells through c-Myc-SMPDL3B.

Elife

2021 May 27

Fan W, Tang S, Fan X

47. Traumatic injury compromises nucleocytoplasmic transport and leads to TDP-43 pathology.

Elife

2021 May 26

Anderson EN, Morera AA, Kour S

48. Biological controls for standardization and interpretation of adaptive immune receptor repertoire profiling.

Elife

2021 May 26

Trück J(#), Eugster A(#), Barennes P(#)

49. The pattern of nodal morphogen signaling is shaped by co-receptor expression.

Elife

2021 May 26

Lord ND(#), Carte AN(#), Abitua PB

50. Genome-wide CRISPRi screening identifies OCIAD1 as a prohibitin client and regulatory determinant of mitochondrial Complex III assembly in human cells.

Elife

2021 May 26

Le Vasseur M, Friedman J, Jost M

51. The molecular coupling between substrate recognition and ATP turnover in a AAA+ hexameric helicase loader.

Elife

2021 May 26

Puri N(#), Fernandez AJ(#), O'Shea Murray VL

52. Beware the algorithm.

Elife

2021 May 26

van Endert P.

53. Phenotypic plasticity underlies local invasion and distant metastasis in colon cancer.

Elife

2021 May 26

Sacchetti A(#), Teeuwssen M(#), Verhagen M(#)

54. Tendon and motor phenotypes in the Crtap(-/-) mouse model of recessive osteogenesis imperfecta.

Elife

2021 May 26

Grol MW, Haelterman NA, Lim J

55. No relationship between frontal alpha asymmetry and depressive disorders in a multiverse analysis of five studies.

Elife

2021 May 26

Kołodziej A, Magnuski M, Ruban A

56. Introducing the MAVEN Leadership Training Initiative to diversify the scientific workforce.

Elife

2021 May 25

Wang YC, Brondolo E, Monane R

57. TRPM channels mediate learned pathogen avoidance following intestinal distention.

Elife

2021 May 25

Filipowicz A, Lalsiamthara J, Aballay A.

58. Post-translational flavinylation is associated with diverse extracytosolic redox functionalities throughout bacterial life.

Elife

2021 May 25

Méheust R(#), Huang S(#), Rivera-Lugo R

59. Perinatal development of innate immune topology.

Elife

2021 May 25

Henneke P, Kierdorf K, Hall LJ

60. Starvation-induced regulation of carbohydrate transport at the blood-brain barrier is TGF-β-signaling dependent.

Elife

2021 May 25

Hertenstein H, McMullen E, Weiler A

61. Mechanical heterogeneity along single cell-cell junctions is driven by lateral clustering of cadherins during vertebrate axis elongation.

Elife

2021 May 25

Huebner RJ(#), Malmi-Kakkada AN(#), Sarıkaya S

62. Detecting adaptive introgression in human evolution using convolutional neural networks.

Elife

2021 May 25

Gower G, Picazo PI, Fumagalli M

63. Optogenetic strategies for high-efficiency all-optical interrogation using blue-light-sensitive opsins.

Elife

2021 May 25

Forli A(#), Pisoni M(#), Printz Y(#)

64. The discriminatory power of the T cell receptor.

Elife

2021 May 25

Pettmann J(#), Huhn A(#), Abu Shah E(#)

65. Information flow, cell types and stereotypy in a full olfactory connectome.

Elife

2021 May 25

Schlegel P(#), Bates AS(#), Stürner T(#)

66. Cellular, circuit and transcriptional framework for modulation of itch in the central amygdala.

Elife

2021 May 25

Samineni VK, Grajales-Reyes JG, Grajales-Reyes GE

67. Introduction to the EQIPD quality system.

Elife

2021 May 24

Bespalov A(#), Bernard R(#), Gilis A(#)

While high risk of failure is an inherent part of developing innovative therapies, it can be reduced by adherence to evidence-based rigorous research practices. Supported through the European Union's Innovative Medicines Initiative, the EQIPD consortium has developed a novel preclinical research quality system that can be applied in both public and private sectors and is free for anyone to use. The EQIPD Quality System was designed to be suited to boost innovation by ensuring the generation of robust and reliable preclinical data while being lean, effective and not becoming a burden that could negatively impact the freedom to explore scientific questions. EQIPD defines research quality as the extent to which research data are fit for their intended use. Fitness, in this context, is defined by the stakeholders, who are the scientists directly involved in the research, but also their funders, sponsors, publishers, research tool manufacturers, and collaboration partners such as peers in a multi-site research project. The essence of the EQIPD Quality System is the set of 18 core requirements that can be addressed flexibly, according to user-specific needs and following a user-defined trajectory. The EQIPD Quality System proposes guidance on expectations for quality-related measures, defines criteria for adequate processes (i.e. performance standards) and provides examples of how such measures can be developed and implemented. However, it does not prescribe any pre-determined solutions. EQIPD has also developed tools (for optional use) to support users in implementing the system and assessment services for those research units that successfully implement the quality system and seek formal accreditation. Building upon the feedback from users and continuous improvement, a sustainable EQIPD Quality System will ultimately serve the entire community of scientists conducting non-regulated preclinical research, by helping them generate reliable data that are fit for their intended use.

68. A phosphorylation of RIPK3 kinase initiates an intracellular apoptotic pathway that promotes prostaglandin(2α)-induced corpus luteum regression.

Elife

2021 May 24

Li D, Chen J, Guo J

69. Design principles of the ESCRT-III Vps24-Vps2 module.

Elife

2021 May 24

Banjade S, Shah YH, Tang S

70. Wnt- and glutamate-receptors orchestrate stem cell dynamics and asymmetric cell division.

Elife

2021 May 24

Junyent S(#), Reeves JC(#), Szczerkowski J

71. Place-cell capacity and volatility with grid-like inputs.

Elife

2021 May 24

Yim MY, Sadun LA, Fiete IR

72. Midbrain dopaminergic inputs gate amygdala intercalated cell clusters by distinct and cooperative mechanisms in male mice.

Elife

2021 May 24

Aksoy-Aksel A, Gall A, Seewald A

73. Erythrocyte CD55 mediates the internalization of Plasmodium falciparum parasites.

Elife

2021 May 24

Shakya B, Patel SD, Tani Y

74. Corticothalamic gating of population auditory thalamocortical transmission in mouse.

Elife

2021 May 24

Ibrahim BA, Murphy CA, Yudintsev G

75. Cross-species analysis defines the conservation of anatomically segregated VMH neuron populations.

Elife

2021 May 21

Affinati AH, Sabatini PV, True C

76. Thirst interneurons that promote water seeking and limit feeding behavior in Drosophila.

Elife

2021 May 21

Landayan D, Wang BP, Zhou J

77. Asymmetric localization of the cell division machinery during Bacillus subtilis sporulation.

Elife

2021 May 21

Khanna K, Lopez-Garrido J, Sugie J

78. Symmetry breaking meets multisite modification.

Elife

2021 May 21

Ramesh V, Krishnan J.

79. Putting organelles in their place.

Elife

2021 May 21

Ulm P, Jantsch V.

80. Perturbation of amygdala-cortical projections reduces ensemble coherence of palatability coding in gustatory cortex.

Elife

2021 May 21

Lin JY, Mukherjee N, Bernstein MJ

81. Amphiphysin I cleavage by asparagine endopeptidase leads to tau hyperphosphorylation and synaptic dysfunction.

Elife

2021 May 21

Zhang X(#), Zou L(#), Meng L

82. Kv1.1 channels regulate early postnatal neurogenesis in mouse hippocampus via the TrkB signaling pathway.

Elife

2021 May 21

Chou SM(#), Li KX(#), Huang MY(#)

83. Conformational specificity of opioid receptors is determined by subcellular location irrespective of agonist.

Elife

2021 May 20

Crilly SE, Ko W, Weinberg ZY

84. Abortive intussusceptive angiogenesis causes multi-cavernous vascular malformations.

Elife

2021 May 20

Li W, Tran V, Shaked I

85. An evolutionary model identifies the main evolutionary biases for the evolution of genome-replication profiles.

Elife

2021 May 20

Droghetti R, Agier N, Fischer G

86. Somatostatin-expressing parafacial neurons are CO(2)/H(+) sensitive and regulate baseline breathing.

Elife

2021 May 20

Cleary CM, Milla BM, Kuo FS

87. Standardized and reproducible measurement of decision-making in mice.

Elife

2021 May 20

International Brain Laboratory; Aguillon-Rodriguez V, Angelaki D, Bayer H

88. Cell-scale biophysical determinants of cell competition in epithelia.

Elife

2021 May 20

Gradeci D(#), Bove A(#), Vallardi G

89. Onset of taste bud cell renewal starts at birth and coincides with a shift in SHH function.

Elife

2021 May 19

Golden EJ, Larson ED, Shechtman LA

90. Glycan-based shaping of the microbiota during primate evolution.

Elife

2021 May 19

Singh S, Bastos-Amador P(#), Thompson JA(#)

91. Voltage-clamp fluorometry analysis of structural rearrangements of ATP-gated channel P2X2 upon hyperpolarization.

Elife

2021 May 19

Andriani RT, Kubo Y.

92. Metal microdrive and head cap system for silicon probe recovery in freely moving rodent.

Elife

2021 May 19

Vöröslakos M(#), Petersen PC(#), Vöröslakos B(#)

93. Single-cell transcriptome analysis defines heterogeneity of the murine pancreatic ductal tree.

Elife

2021 May 19

Hendley AM, Rao AA(#), Leonhardt L(#)

94. Competitive coordination of the dual roles of the Hedgehog co-receptor in homophilic adhesion and signal reception.

Elife

2021 May 18

Yang S(#), Zhang Y(#), Yang C(#)

95. HDAC1 SUMOylation promotes Argonaute-directed transcriptional silencing in C. elegans.

Elife

2021 May 18

Kim H(#), Ding YH(#), Zhang G

96. The severity of microstrokes depends on local vascular topology and baseline perfusion.

Elife

2021 May 18

Schmid F, Conti G, Jenny P

97. Polymerization of misfolded Z alpha-1 antitrypsin protein lowers CX3CR1 expression in human PBMCs.

Elife

2021 May 18

Tumpara S, Ballmaier M, Wrenger S

98. Multi-step vs. single-step resistance evolution under different drugs, pharmacokinetics, and treatment regimens.

Elife

2021 May 18

Igler C, Rolff J, Regoes R.

99. R7 photoreceptor axon targeting depends on the relative levels of lost and found expression in R7 and its synaptic partners.

Elife

2021 May 18

Douthit J(#), Hairston A(#), Lee G

100. Calibration of cell-intrinsic interleukin-2 response thresholds guides design of a regulatory T cell biased agonist.

Elife

2021 May 18

Glassman CR, Su L, Majri-Morrison SS

101. Local circuit allowing hypothalamic control of hippocampal area CA2 activity and consequences for CA1.

Elife

2021 May 18

Robert V, Therreau L, Chevaleyre V

102. Psychomotor impairments and therapeutic implications revealed by a mutation associated with infantile Parkinsonism-Dystonia.

Elife

2021 May 18

Aguilar JI, Cheng MH, Font J

103. The hepcidin regulator erythroferrone is a new member of the erythropoiesis-iron-bone circuitry.

Elife

2021 May 18

Castro-Mollo M(#), Gera S(#), Ruiz-Martinez M

BACKGROUND: Erythroblast erythroferrone (ERFE) secretion inhibits hepcidin expression by sequestering several bone morphogenetic protein (BMP) family members to increase iron availability for erythropoiesis. METHODS: To address whether ERFE functions also in bone and whether the mechanism of ERFE action in bone involves BMPs, we utilize the Erfe-/- mouse model as well as β-thalassemic (Hbbth3/+) mice with systemic loss of ERFE expression. In additional, we employ comprehensive skeletal phenotyping analyses as well as functional assays in vitro to address mechanistically the function of ERFE in bone. RESULTS: We report that ERFE expression in osteoblasts is higher compared with erythroblasts, is independent of erythropoietin, and functional in suppressing hepatocyte hepcidin expression. Erfe-/- mice display low-bone-mass arising from increased bone resorption despite a concomitant increase in bone formation. Consistently, Erfe-/- osteoblasts exhibit enhanced mineralization, Sost and Rankl expression, and BMP-mediated signaling ex vivo. The ERFE effect on osteoclasts is mediated through increased osteoblastic RANKL and sclerostin expression, increasing osteoclastogenesis in Erfe-/- mice. Importantly, Erfe loss in Hbbth3/+mice, a disease model with increased ERFE expression, triggers profound osteoclastic bone resorption and bone loss. CONCLUSIONS: Together, ERFE exerts an osteoprotective effect by modulating BMP signaling in osteoblasts, decreasing RANKL production to limit osteoclastogenesis, and prevents excessive bone loss during expanded erythropoiesis in β-thalassemia. FUNDING: YZG acknowledges the support of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (R01 DK107670 to YZG and DK095112 to RF, SR, and YZG). MZ acknowledges the support of the National Institute on Aging (U19 AG60917) and NIDDK (R01 DK113627). TY acknowledges the support of the National Institute on Aging (R01 AG71870). SR acknowledges the support of NIDDK (R01 DK090554) and Commonwealth Universal Research Enhancement (CURE) Program Pennsylvania.

104. Integrated sensing of host stresses by inhibition of a cytoplasmic two-component system controls M. tuberculosis acute lung infection.

Elife

2021 May 18

Buglino JA, Sankhe GD, Lazar N

105. Avoiding culture shock with the SARS-CoV-2 spike protein.

Elife

2021 May 18

Hale BG.

106. Modeling the impact of racial and ethnic disparities on COVID-19 epidemic dynamics.

Elife

2021 May 18

Ma KC, Menkir TF, Kissler S

107. PIE-1 SUMOylation promotes germline fates and piRNA-dependent silencing in C. elegans.

Elife

2021 May 18

Kim H(#), Ding YH(#), Lu S

108. ß-arrestin 2 germline knockout does not attenuate opioid respiratory depression.

Elife

2021 May 18

Bachmutsky I(#), Wei XP(#), Durand A

109. Random sub-diffusion and capture of genes by the nuclear pore reduces dynamics and coordinates inter-chromosomal movement.

Elife

2021 May 18

Sumner MC, Torrisi SB, Brickner DG

110. Live-imaging of endothelial Erk activity reveals dynamic and sequential signalling events during regenerative angiogenesis.

Elife

2021 May 18

Okuda KS, Keyser MS, Gurevich DB

111. The organizational principles of de-differentiated topographic maps in somatosensory cortex.

Elife

2021 May 18

Liu P(#), Chrysidou A(#), Doehler J

112. Novel cell types and developmental lineages revealed by single-cell RNA-seq analysis of the mouse crista ampullaris.

Elife

2021 May 18

Wilkerson BA, Zebroski HL, Finkbeiner CR

113. HSPCs display within-family homogeneity in differentiation and proliferation despite population heterogeneity.

Elife

2021 May 18

Tak T(#), Prevedello G(#), Simon G

114. PHAROH lncRNA regulates Myc translation in hepatocellular carcinoma via sequestering TIAR.

Elife

2021 May 18

Yu AT, Berasain C, Bhatia S

115. Integrated transcriptomic and neuroimaging brain model decodes biological mechanisms in aging and Alzheimer's disease.

Elife

2021 May 18

Adewale Q, Khan AF, Carbonell F

116. The crystal structure of bromide-bound GtACR1 reveals a pre-activated state in the transmembrane anion tunnel.

Elife

2021 May 17

Li H(#), Huang CY(#), Govorunova EG

117. Signaling levels mold the RAS mutation tropism of urethane.

Elife

2021 May 17

Li S, Counter CM.

118. Danger zone.

Elife

2021 May 17

Butt Z, Prior I.

119. Clustered functional domains for curves and corners in cortical area V4.

Elife

2021 May 17

Jiang R, Andolina IM, Li M

120. Do wealth and inequality associate with health in a small-scale subsistence society?

Elife

2021 May 14

Jaeggi AV(#), Blackwell AD(#), von Rueden C

121. Functional dynamic genetic effects on gene regulation are specific to particular cell types and environmental conditions.

Elife

2021 May 14

Findley AS, Monziani A, Richards AL

122. Inbreeding in a dioecious plant has sex- and population origin-specific effects on its interactions with pollinators.

Elife

2021 May 14

Schrieber K, Paul SC, Höche LV

123. A TORC1-histone axis regulates chromatin organisation and non-canonical induction of autophagy to ameliorate ageing.

Elife

2021 May 14

Lu YX, Regan JC, Eßer J

124. Distinct protocerebral neuropils associated with attractive and aversive female-produced odorants in the male moth brain.

Elife

2021 May 14

Kymre JH(#), Liu X(#), Ian E

125. Spatiotemporal control of cell cycle acceleration during axolotl spinal cord regeneration.

Elife

2021 May 14

Cura Costa E(#), Otsuki L(#), Rodrigo Albors A

126. A subcellular map of the human kinome.

Elife

2021 May 14

Zhang H, Cao X, Tang M

127. Low-dimensional learned feature spaces quantify individual and group differences in vocal repertoires.

Elife

2021 May 14

Goffinet J, Brudner S, Mooney R

128. Dopamine differentially modulates the size of projection neuron ensembles in the intact and dopamine-depleted striatum.

Elife

2021 May 13

Maltese M, March JR, Bashaw AG

129. Sex differences in biological aging with a focus on human studies.

Elife

2021 May 13

Hägg S, Jylhävä J.

130. Rapid adaptation of endocytosis, exocytosis, and eisosomes after an acute increase in membrane tension in yeast cells.

Elife

2021 May 13

Lemière J(#), Ren Y(#), Berro J.

131. Single-PanIN-seq unveils that ARID1A deficiency promotes pancreatic tumorigenesis by attenuating KRAS-induced senescence.

Elife

2021 May 13

Liu S(#), Cao W(#), Niu Y(#)

132. Propensity for somatic expansion increases over the course of life in Huntington disease.

Elife

2021 May 13

Kacher R, Lejeune FX, Noël S

133. The effect of host community functional traits on plant disease risk varies along an elevational gradient.

Elife

2021 May 13

Halliday FW(#), Jalo M(#), Laine AL.

134. Permeabilization-free en bloc immunohistochemistry for correlative microscopy.

Elife

2021 May 13

Fulton KA, Briggman KL.

135. Bundle-specific associations between white matter microstructure and Aβ and tau pathology in preclinical Alzheimer's disease.

Elife

2021 May 13

Pichet Binette A, Theaud G, Rheault F

136. A non-genetic, cell cycle-dependent mechanism of platinum resistance in lung adenocarcinoma.

Elife

2021 May 13

Gonzalez Rajal A, Marzec KA, McCloy RA

137. Structural basis for allosteric control of the SERCA-Phospholamban membrane complex by Ca(2+) and phosphorylation.

Elife

2021 May 12

Weber DK, Reddy UV, Wang S

138. NHR-49/PPAR-α and HLH-30/TFEB cooperate for C. elegans host defense via a flavin-containing monooxygenase.

Elife

2021 May 12

Wani KA, Goswamy D, Taubert S

139. Homoplasy in the evolution of modern human-like joint proportions in Australopithecus afarensis.

Elife

2021 May 12

Prabhat AM, Miller CK, Prang TC

140. Adapting non-invasive human recordings along multiple task-axes shows unfolding of spontaneous and over-trained choice.

Elife

2021 May 11

Takagi Y, Hunt LT, Woolrich MW

141. A developmental framework linking neurogenesis and circuit formation in the Drosophila CNS.

Elife

2021 May 11

Mark B, Lai SL, Zarin AA

142. EXOC1 plays an integral role in spermatogonia pseudopod elongation and spermatocyte stable syncytium formation in mice.

Elife

2021 May 11

Osawa Y(#), Murata K(#), Usui M

143. Differential spatiotemporal development of Purkinje cell populations and cerebellum-dependent sensorimotor behaviors.

Elife

2021 May 11

Beekhof GC(#), Osório C(#), White JJ

144. Limited inhibition of multiple nodes in a driver network blocks metastasis.

Elife

2021 May 11

Yesilkanal AE, Yang D, Valdespino A

145. Integrative transcriptomic analysis of tissue-specific metabolic crosstalk after myocardial infarction.

Elife

2021 May 11

Arif M(#), Klevstig M(#), Benfeitas R

146. Coronary plaque composition influences biomechanical stress and predicts plaque rupture in a morpho-mechanic OCT analysis.

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2021 May 11

Milzi A(#), Lemma ED(#), Dettori R(#)

147. Enhanced excitability of cortical neurons in low-divalent solutions is primarily mediated by altered voltage-dependence of voltage-gated sodium channels.

Elife

2021 May 11

Martiszus BJ, Tsintsadze T, Chang W

148. The role of sigma 1 receptor in organization of endoplasmic reticulum signaling microdomains.

Elife

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Zhemkov V, Ditlev JA, Lee WR

149. In vitro reconstitution reveals major differences between human and bacterial cytochrome c synthases.

Elife

2021 May 11

Sutherland MC(#), Mendez DL(#), Babbitt SE(#)

150. KSR1- and ERK-dependent translational regulation of the epithelial-to-mesenchymal transition.

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2021 May 10

Rao C, Frodyma DE, Southekal S

151. Chromatin structure-dependent histone incorporation revealed by a genome-wide deposition assay.

Elife

2021 May 10

Tachiwana H, Dacher M, Maehara K

152. A new player in the dermis.

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Egawa G, Kabashima K.

153. A novel ATP dependent dimethylsulfoniopropionate lyase in bacteria that releases dimethyl sulfide and acryloyl-CoA.

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Li CY(#), Wang XJ(#), Chen XL

154. Recovery of consciousness and cognition after general anesthesia in humans.

Elife

2021 May 10

Mashour GA, Palanca BJ, Basner M

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